Welcome!
Our Faculty of Pharmacy Unit is part of the HiLIFE platform Drug discovery, chemical biology and screening. We offer a versatile selection of support for screening projects and follow-up studies, such as:
Please note that if you have used our (DDCB-PHAR) services, you must acknowledge this in publications by adding the following (or similar) statement to the acknowledgements: “The facilities and expertise of the DDCB Unit at the Faculty of Pharmacy, University of Helsinki, supported by HiLIFE and Biocenter Finland, is gratefully acknowledged.” Please send a copy of such publication to paivi.tammela@helsinki.fi to help us in reporting to the university the use of our services.
Instructions on iLab both for researchers and PIs, as well as instrument list and detailed service descriptions can be found from our core facility website
| Päivi Tammela | Head of screening unit | +358504480886 | paivi.tammela@helsinki.fi |
| Hours | Location |
|
Monday - Friday 8 am - 5 pm |
Visiting address: Biocenter 2, Viikki campus, University of Helsinki, Viikinkaari 5, E-tower
|
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Päivi Tammela |
+358 50 4480886
|
paivi.tammela@helsinki.fi
|
||
| Polina Ilina |
Screening services
|
+358504480790
|
polina.ilina@helsinki.fi
|
|
| Kai Puhakainen |
Screening services
|
+358504755987
|
kai.puhakainen@helsinki.fi
|
|
| Juho Heininen |
LC-MS services
|
+358503597041
|
juho.heininen@helsinki.fi
|
|
| Heidi Kidron |
heidi.kidron@helsinki.fi
|
|||
| Ashenafi Legehar |
Computational services
|
+358504477948
|
ashenafi.legehar@helsinki.fi
|
|
| Henri Xhaard |
Head of unit, Computational services
|
+358504480878
|
henri.xhaard@helsinki.fi
|
| Service list |
| ► Bioactivity assays (3) | |||
| Name | Description | Price | |
|---|---|---|---|
| Antibacterial activity assay (one plate) - Per 96 well plate |
Determination of antibacterial activity (compounds, natural products etc.) by broth microdilution assay, screening and dose response. In screening assay 16 samples per plate can be tested in triplicate at the single concentration, and in dose response assay 2 samples at 8 concentrations. Primarily, user is expected to provide the bacterial strain for the assays. Availability of strains can also be inquired from the research group of prof. Tammela by email (paivi.tammela@helsinki.fi) or when submitting project request in iLab.
|
Inquire | |
| Cytotoxicity assay (one plate) - Per 96 well plate |
Determination of cytotoxicity(compounds, natural products etc.) by CellTiterGlo assay, screening and dose response. In screening assay, 18 samples per plate can be tested in triplicate at the single concentration, and in dose response assay 2 samples at 9 concentrations in triplicate. Primarily, user is expected to provide the cell line for the assays. Availability of cell lines can also be inquired from the research group of prof. Tammela by email (paivi.tammela@helsinki.fi) or when submitting project request in iLab.
|
Inquire | |
| Custom assays |
Custom assays (e.g. custom pipetting protocols using Biomek i7, custom liquid dispensing with Mantis Liquid Handler, imaging protocols using Cytation 5 imaging reader, automated and semi-automated workflows utilizing multiple instruments, etc.)
Please initiate Project request to discuss with our core facility staff about your custom assay and ask for a quote. |
Inquire | |
| Name | Price | |
|---|---|---|
| Varioskan LUX (Biocenter 2, room 4067) (2 instruments) | ||
| ChemiDoc MP (Biocenter 2, room 4067) | ||
| NanoDrop One (Biocenter 2, room 4069) | ||
| LC-MS (Biocenter 2, Room 1079) (Two LC-MS instruments) | ||
| Biomek i7 (Biocenter 2, room 4068) | ||
| Mantis Liquid Handler (Biocenter 2, room 4080) | ||
| Cytation 5 & BioSpa (Biocenter 2, room 4068) | ||
| MultiFlo FX (Biocenter 2, room 4068) | ||
| Electroporator (Biocenter 2, room 4069) | ||
| Omnilog (Biocenter 2, room 4080) | ||
| Biorad NGC System (Biocenter 2, room 4058a) | ||
| LC-MS | ||
| BioSpa (Biocenter 2, room 4068) | ||
